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Affecting approximately 50% of patients with diabetes, DN is predominantly characterized by distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, often resulting in diabetic foot ulcers and lower-limb amputations

Researchers using IGF-1 LR3 can achieve consistent, reproducible IGF-1R activation without needing to account for variable IGFBP levels across different serum lots or culture conditions

By when can I see the results

Results require ongoing maintenance infusions to sustain, as improvements diminish after approximately six months without continued treatment

Although some theorize that Tesamorelin's effects might be related to molecules like IGF-1, the study did not find a notable connection between changes in IGF-1 levels and shifts in muscle size or density