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On the one hand, it promotes ferroptosis by inhibiting the expression of SLC7A11 or promoting the expression of metabolism-related genes spermidine/Spermine N1-acetyltransferase 1 ( SAT1 ) and glutaminase 2 ( GLS2 ) [73,74,75,76]

A similar diabetic model, echocardiographic and hemodynamic studies revealed that alogliptin (12.5 mg/kg/d for 12 weeks) decreased diastolic dysfunction, ventricular hypertrophy and interstitial fibrosis

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Journal of Nutrition

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