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It stimulates blood vessel and nerve outgrowth and increases collagen, elastin, and glycosaminoglycan synthesis

However, whether GPX4 can be a putative target for reducing neuronal injury in epileptic brain, especially in PTE, is yet to be verified in animal models and cell epilepsy models

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Nature 616, 190198

FIGURE 8 FIGURE 9 Conclusion By using the GPX4 activator compound as chemical probe, we demonstrated that up-regulation of GPX4 activity can reduce the production of inflammatory agents and promote inflammation resolution ( Figure 10 )