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Delta-Sleep-Inducing Peptide (DSIP) Delta-sleep-inducing peptide (DSIP) is a naturally occurring neuropeptide consisting of nine amino acids with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Published in Diabetologia (Blher and colleagues, NCT04153929), this Phase 2 trial randomized 413 adults with type 2 diabetes on background metformin to survodutide across several once-weekly or twice-weekly dose groups, to placebo, or to open-label semaglutide up to 1.0 mg once weekly

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Larger TLK and LKCA indicate sharper kyphotic deformities, which can increase anterior shear forces on the discs, promoting degeneration

Again, in Table 2, all independent variables were taken into multiple analyses by linear regression to adjust for the effect of suicide risk (primary exposure) on glutathione levels (outcome)