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456,457 DtxR family of proteins are characterized by an N-terminal DNA-binding domain, an interfacial domain which contains two metal-binding sites, and a third C-terminal SH3 (Src homology 3)-like domain not present in all DtxR family crystal structures

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Senomorphics An alternative approach of the use of senolytics, which clear senescent cells, is the use of senomorphics to ameliorate their SASP (summarized in: (55))