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Antigen retrieval was performed by immersing the slides in preheated Universal buffer for 20 min, in a water bath set at +95 C followed by a cool down phase for 30 min on the bench

105 It suppresses the biological activity of skin cells and the expression of cytokines, resulting in immune dysfunction of the wound, dysplasia of granulation tissue, and reepithelialization disorders, thus delaying wound healing

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H 2 O 2 is an efficient activator of the redox-regulated proinflammatory transcription factor NF-KB, where redox-regulation activates upstream kinases P13K and NIK leading to NF-KB translocation and promotor binding