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DLK1 is frequently upregulated in myelodysplastic syndrome (MDS) patients compared to non-leukemic individuals
BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL)
and inhibits NF-κB
Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase
Polyglutamylation is a PTM that occurs when secondary glutamate side chains are formed on
anti-Periostin, mAb (Stiny-1) HY-100558 DLK1 is frequently upregulated inPeriostin is a 90 kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine rich region, an EMI domain (protein protein interactions), four tandem fasciclin like domains that are responsible for integrin binding, and a C terminal region. Periostin was originally isolated as an osteoblast specific factor that functions as a cell adhesion molecule for pre osteoblasts and in osteoblast recruitment, attachment and
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