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By contrast, mTORC2 regulates the activity of RhoA to accelerate Th2 cell differentiation [66]

This pathway: Promotes synaptogenesis the formation of new synaptic connections between neurons Mimics BDNF activity downstream effects on neuronal survival, plasticity, and growth Enhances hippocampal function the hippocampus is critical for memory formation and retrieval Crosses the blood-brain barrier unlike BDNF itself, Dihexa is small enough to penetrate the BBB The result is enhanced neural plasticity the brain's ability to reorganize and form new connections, which underlies learning, memory, and cognitive performance

Persistent increase in oxygen consumption and impaired neurovascular coupling after spreading depression in rat neocortex

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