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This result eliminates the possibility that the survivors of the high temperature (42 O C) in the first experiment a are either heat-tolerant mutants or persistor-like cells that behave similarly to persistors of antibiotic treatments

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The reason for this sensitivity is unknown, although two general possibilities may be considered, namely the high susceptibility of the brain to oxidative stress due to its high oxygen consumption, and the possibility that GSH may be a neuromodulator or neurotransmitter and may thus be essential for central nervous system activities

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