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The symptoms seem to disappear temporarily after visiting doctors and getting medications, only to resurface once the medication stops

95% CI: 0.05, 0.13

Most patients complete an initial protocol of 36 months

Glutathione and Hypothyroidism: Restoring Redox Balance In hypothyroidism - whether autoimmune (Hashimoto's) or non-autoimmune - the reduced metabolic rate paradoxically also creates oxidative stress, through different mechanisms: *Reduced mitochondrial efficiency - slower metabolism generates more electron leakage and ROS per unit of energy produced *Impaired antioxidant enzyme activity - thyroid hormones regulate the expression of antioxidant enzymes including GPx and SOD

Physiol Rev (2002) 82(1):4795