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Description

& Schindowski, K

The peptide was originally derived from the protein structure of Epithalamin, a pineal gland extract studied extensively in Russian gerontology research since the 1960s

demonstrated thaterastin and RSL3 induced renal tubular cell death accompanied by high ACSL4 levels in vitro , while the ACSL4 inhibitor rosiglitazone improved the survival rate and alleviated kidney injury in diabetic nephropathy mice, and decreased lipid peroxidation products and iron content (Wang et al., 2020)