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Imoto S, et al

Rather than being associated with a single mechanism, the peptide appears to interact with multiple signaling pathways that influence how tissues respond to stress and structural disruption

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Also CPT analogues showed a good correlation between polarity and BCRP-association, where highly polar compounds showed substrate specificity

It would seem likely that GSHee drives fr by actions within the carotid bodies by mechanisms including direct effects on neurotransmitter release from primary glomus cells