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Ronaldson PT, Bendayan R

RNA modifications add a third tier: aberrant m6A deposition by METTL3/14 or its removal by FTO perturbs stability of mRNAs encoding DDR modulators, such as RAD51 and CHEK1 [121]

In the hindlimb unloading-induced atrophy model, reduced mitochondrial respiration, calcium retention capacity, and increased oxidative stress are closely associated with muscle function decline, suggesting that maintaining mitochondrial function is critical for muscle recovery (83)

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