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Furthermore, it is essential to elucidate the specific pathways of cross-organ migration of oral microbiota, their colonization conditions, and the regulatory details of their influence on gut-brain axis signaling, including immune factors, metabolites, and neurotransmitters

While these findings dont directly translate to humans, they raise legitimate concerns about reproductive health, endocrine disruption, and metabolic stress with prolonged, high-dose usage

10.1089/cbr.2020.3734 290 ZhouX.JiaoD.DouM.ZhangW.LvL.ChenJ.et al (2020b)

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