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The European Respiratory Journal Geiler J at al., (2010), N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus, Biochemical Pharmacology McCarty at al.(2020), Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus, Progress in Cardiovascular Diseases Palacio at al., (2011) Anti-inflammatory properties of N-acetylcysteine on lipopolysaccharide-activated macrophages, Inflammation Research Sadowska et al.,(2006), Role of N-acetylcysteine in the management of COPD, International Journal of Chronic Obstructive Pulmonary Disease Schmitt et al.,(2015), Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study, Redox Biology Zhang et al.,(2018), N-acetylcysteine improves oxidative stress and inflammatory response in patients with community acquired pneumonia, Medicine

FDAs Office of Inspections and Investigations (OII) Field Science Laboratories centrally manages the program, including interacting with DOD and coordinating laboratory work

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