In human dermal fibroblast cultures, Pal-KTTKS stimulated type I collagen synthesis by 117%, type III collagen by 327%, and hyaluronic acid production by 267%, as measured by immunoassay and ELISA at a concentration of 3 ppm
The ER, which is responsible for essential cellular functions including protein folding and calcium storage/signaling, can experience disturbances in the folding environment, leading to the accumulation of misfolded proteins and subsequent ER stress
doi: 10.1016/j.cmet.2017.04.015
These include proteins such as GGP1, an enzyme with a putative glutamine amidotransferase domain that has been implicated in the removal of the Glu residue from a GS-conjugate during glucosinolate synthesis (Geu-Flores et al., 2009)
If you do, it could release all the medicine at once and increase the risk of side effects