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In addition, this ATM increase was prevented by pre-incubation of cells with antioxidants

Safety and metabolism of long-term administration of NIAGEN (nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults

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These results indicate that HA-RM-Cel-BR has favorable biosafety in vivo, and significantly reduces the hepatotoxicity of Cel