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Those same miRNAs also affect tumor suppressor genes.[ref] While a lot more research is needed here, the impact of miRNA on both tumor suppressors and MTHFR may be part of why folate is both beneficial for preventing cancer and then detrimental during some types of cancer

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B-Complex Vitamin B Complex is a group of eight essential water-soluble vitamins that play vital roles in various physiological functions, including energy production, metabolism, nerve function, and red blood cell formation

At the same time, the activity of antioxidant enzymes (SOD, GPX, GR) in cardiomyocytes is weaker than that in other organs [17], further aggravating the susceptibility to this injury