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[46], the rat was handled and inverted in a way that ensure preventing the movement of the head and the neck is parallel to the floor, the micropipette tip is near the nostril at 45-degree angle

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Notably, research commonly distinguishes between hyperplasia (increased cell number) and hypertrophy (increased cell size)

Common findings include reduced microbial diversity, depletion of short-chain fatty acid (SCFA)-producing genera, and enrichment of pro-inflammatory taxa

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