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(125) suggested an increased risk of death with the use of large doses of vitamin E, yet lower than the UL

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Men and women 60 years or older have average dietary intakes of 5.6 g/day and 3.7 g/day, respectively (126)

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Vitamin A: metabolism, dietary sources, functions, and signaling pathways The main pro-vitamin is -carotene and is transformed to its active form of vitamin A in the intestine where it is cleaved by -carotene dioxygenase and by retinaldehyde reductase and finally reduced to retinol