The CEL files (data files used by Affymetrix software, used by the Broad Institute) were processed with MAS5 (Microarray Analysis Suite 5 software, Affymetrix, Santa Clara, CA, USA) and background correction
All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)
Studies examining links between TB500 and integrin linked kinase suggest potential involvement in pathways related to cell adhesion, structural organization, and communication between cells and their surrounding matrix
This version is considered the poorest and therefore cheapest version of vitamin B12
- High-dose oral B12 treatment Instead of taking the injection route, a provider may prescribe a high-dose B12 oral treatmenta pill, capsule, or lozenge containing a higher concentration of B12 than your average over-the-counter (OTC) supplement