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To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets

The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus

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One 1994 topical trial in one specific ulcer population is a data point, not a general claim, and the product it studied was never approved

Combination approaches that pair GSH depletion with ferroptosis induction, immunotherapy, or chemotherapy may help overcome resistance, while standardized manufacturing and rigorous toxicity evaluation will be critical for regulatory approval