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The copper ion may dissociate from the GHK tripeptide, and free copper ions are pro-oxidant

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Toxicol Vitro 26(7):11221128 Cordaro M, DAmico R, Fusco R, Peritore AF, Genovese T, Interdonato L, Impellizzeri D (2022) Discovering the effects of fisetin on NF-B/NLRP-3/NRF-2 molecular pathways in a mouse model of vascular dementia induced by repeated bilateral carotid occlusion

doi: 10.1111/j.1365-2796.2007.01809.x 15