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Thanks to its higher affinity for the p53 domain, this peptide disrupts the interaction between natural FOXO factors and p53, leading to the induction of apoptosis in senescent cells [127]

The combination of LC supplementation and RT increased circulating SPARC and decorin levels but did not affect the other studied markers

Quantitative, targeted analysis of gut microbiota derived metabolites provides novel biomarkers of early diabetic kidney disease in type 2 diabetes mellitus patients

Addressing these challenges requires a multifaceted approach that prioritizes safety, effective treatment strategies, and seamless integration into clinical practice