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Normally, NAPQI is efficiently scavenged by hepatic GSH stores in hepatocytes

Worthley et al., 2007) in the oxygenase domain of eNOS (Kondrikov et al., 2010)

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Because the lungs have a dense capillary network, absorption is efficient, but the distribution pattern is different from an injection or infusion nebulized glutathione concentrates initially in respiratory tissue before entering broader circulation

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