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(NOTE: The results were replicated in a separate study using a different NNMT inhibitor, also observing the normalization of tolerance to glucose and increased insulin sensitivity) Already, were seeing some strong interest in using 5-Amino 1MQ to treat obesity and other metabolic diseases in US veterans
(Scientific Reports, 2022) showed that the combination of 5-Amino-1MQ + caloric restriction establishes a distinct cecal microbial profile, normalizing the microbiome to the levels of lean control mice, whereas caloric restriction alone fails to do so
By targeting specific cellular pathways, it may support fat reduction, improve energy balance, and promote overall metabolic health
Adjusting the dose and frequency is key in the maintenance phase
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