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IGF-1 has an A and B chain connected by disulphide bonds, its similarity to insulin means it can bind with low affinity to the insulin receptor [1]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 296.Udo H., Hamasu K., Furuse M., Sugiyama H

Patients often notice smoother, brighter skin, with fine lines and wrinkles softening over time