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Answer: Good candidates are adults struggling with persistent hunger, a stalled response to GLP-1 medications, insulin resistance, or a long history of weight cycling, who want to address the hormonal driver of appetite rather than rely on restriction alone

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No evidence of harm is not the same as evidence of no harm. It just means nobody has looked

Inflammasome complexes, particularly NLRP3, have emerged as key regulators of this inflammatory response

doi: 10.1007/s00210-024-03640-4 308 BanerjeePSahooAAnandSBirAChakrabartiS