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Diagnosis could be challenging as early manifestations of acute acetaminophen hepatotoxicity are nonspecific and patients with repeated overdose (chronic poisoning) tend to present late , and such hepatotoxicity may have already evolved

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As explained in the FY 2006 IPPS final rule (70 FR 47396 through 47398), beginning with FY 2006, we have used the percentage increase in the IPPS operating market basket to update the target amounts for children's hospitals, the 11 cancer hospitals, and RNHCIs

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