Epidemiology of atherosclerosis and the potential to reduce the global burden of atherothrombotic disease
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Supports cognitive ability, metabolic capacity, central nervous system, oxygenation, detoxification, and immune functions
A recent trial comparing IV glutathione to IV N-acetylcysteine found the former to be more effective in preventing contrast-induced nephropathy
1 Introduction Alzheimers disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, memory loss, and neuropsychiatric symptoms, representing one of the most critical global public health challenges of the 21st century ( In this context, ferroptosisa newly defined, regulated cell death modality driven by iron-dependent lipid peroxidationhas rapidly emerged as a frontier and focus in AD research ( Ferroptosis, a regulated form of cell death, plays a significant role in various pathological conditions, including neurodegeneration, cancer, and ischemiareperfusion injury ( Figure 1 ) ( Figure 1 This review aims to systematically elucidate the central role of iron dyshomeostasis and the ferroptosis process it drives in the pathogenesis of Alzheimers disease
