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Treatments are customized, and weekly or monthly doses may be recommended based on individual needs

The FDA-approved labeling for naloxone has the following precaution about use during pregnancy: Naloxone should be used in pregnancy only if clearly needed. The administration of naloxone is appropriate, however, for pregnant patients who have serious signs of potential meperidine toxicity, such as respiratory depression, systemic hypotension, or unresponsiveness

In addition, medications, toxins, autoimmune hepatitis, or Wilson disease may cause acute or chronic hepatitis

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