The publication reported body-weight and glycemic endpoints that were qualitatively consistent with REDEFINE 1, with the combination arm favored over placebo on the reported measures
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Product Specifications Detailed Mechanism of Action AOD-9604 is designed to replicate the lipolytic C-terminal tail of growth hormone while excluding the sequence regions responsible for IGF-1 elevation and insulin antagonism
Pretreatment with PB (30 mg/kg) and glycitin [F (5, 30) = 8.997, P = 0.0039] at the doses of 5, 10 and 20 mg/kg (P = 0.0026, P = 0.0262, P = 0.0146, and P = 0.0145 respectively, Figure 5A) remarkably reduced the MDA level in comparison with the CN group