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In a model of amyotrophic lateral sclerosis (ALS) caused by C9orf72 gene mutations, the pathogenic poly-dipeptide GA50 directly binds to and inhibits SQOR, leading to excessive NLRP3 inflammasome activation in microglia and consequent mitochondrial dysfunction ( A growing body of preclinical work supports this strategy: boosting SQOR activity or reducing H 2 S can protect the nervous system

497 Similarly, NsrR utilizes the 4Fe4S cluster as a NO-sensing module

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See the end of this leaflet for a complete list of ingredients in NASCOBAL

Promotes detoxification: Glutathione helps to detoxify the body by binding to toxins and helping to remove them from the system