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It also indicates that NMN's NAD+ production may be more closely tied to the activity and health of the microbiome than was previously thought

An MTHFR variant does not directly measure current SAM, SAH, methylation capacity, oxidative stress, glutathione status or mitochondrial function

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What to ask your clinic checklist (the questions that separate hype from medicine) If a clinic (or protocol) is credible, they should be comfortable with these questions: What is the specific diagnosis or goal this stack addresses