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Short-term (up to 4 weeks) : Brighter skin tone, better hydration, and increased energy levels Medium-term (13 months) : Reduced hyperpigmentation, more even skin tone, improved immunity, and sharper mental focus Long-term (over 3 months) : More pronounced skin brightening, anti-ageing effects, and liver health support To maintain these outcomes, patients are encouraged to: Stay hydrated by drinking 810 glasses of water daily Follow a diet rich in antioxidant-packed foods Use a broad-spectrum sunscreen (SPF 30+) every day While the improvements can be impressive, they are not permanent

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J Clin Invest , 1988