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reported lower serum calcium and ferritin, lower HDL cholesterol, and higher LDL cholesterol levels in patients with PG vs controls.20 Premature graying has been linked to early cardiovascular disease, and dyslipidemia may serve as a connecting factor.5 Furthermore, lower vitamin D levels have been reported in patients with PG, although without statistically significant associations.20,27 Regarding copper, lower levels have been observed in PG patients vs controls, but without statistical significance.28,29 Comorbidities Several studies have reported a higher prevalence of atopic diathesis in patients with PG.20,26,30 Das et al
Glutathione is crucial for skin health, immune system protection, and brain function because it neutralizes free radicals, regenerates other antioxidants, and promotes detoxification
A significantly high content of I is found in leukocytes that participate in immunity and produce iodine-containing radicals
For therapeutic uses of drugs that can cause hypersensitivity reactions, the risk of hypersensitivity development is often weighted against the therapeutic benefit of the drug, given that subsequent accidental or unintentional exposure to the same molecule would be unlikely
