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When levels of intracellular ADP & ATP rise to excessive levels, cells pump these nucleotides into the extracellular space as a protective measure, whereupon they are converted consecutively to AMP by CD39 and then AMP is converted to adenosine by CD73 (Figure 8)

Later that year, she began experiencing migraines

These results could be explained by a longer reproductive window or by a shifting of the window, and the lack of association with childlessness indicates that some compensatory mechanisms exist

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258 In a meta-analysis of randomized controlled trials investigating various interventions in women with poor ovarian response undergoing IVF, the pooled findings from two trials using DHEA therapy, at 25 mg three times daily, showed it increased the odds of pregnancy nearly 2.5-fold