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1 Aged Muscle Stem Cell Rejuvenation Neelakantan et al., Biochemical Pharmacology (2019) In a follow-up study, the authors tested whether NNMT inhibition could reverse the age-related decline in muscle stem cell (satellite cell) function

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None had a placebo control group

Acute symptoms such as fatigue may improve relatively quickly, whereas neurological symptoms like paraesthesia (pins and needles) or cognitive difficulties typically require longer treatment courses