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General principles Start low: Begin with minimum effective dose Assess tolerance for 2-4 weeks Increase if needed and tolerated Cycle appropriately: Growth hormone peptides: Can use 3-6+ months continuously IGF-1 LR3: Must cycle 4-6 weeks on, 4-6 weeks off Healing peptides: Can use continuously or cycle based on need Monitor progress: Track strength (weights, reps) Monitor body composition Watch for side effects Adjust dosing based on results Timing relative to training Pre-workout: IGF-1 LR3 (nutrient partitioning) Optional: GHRP-6 (some users prefer) Post-workout: IGF-1 LR3 (muscle building) BPC-157 (recovery) Before bed: CJC-1295 + Ipamorelin (GH release during sleep) Growth happens during sleep Throughout day: BPC-157 (twice daily) TB-500 (based on weekly total) Learn proper injection technique in our how to inject peptides guide and mixing protocols in our how to reconstitute peptides guide

Apart from clinical studies using IGF-1 antagonists as anti-cancer drugs, testing antagonists for their ability to block IGF-1 action in growing bone is an important area of research

[PubMed] [Karger] Ravasi G, Pelucchi S, Greni F, et al

Jung J, Shin H, Bang S, Mok HJ, Suh CS, Kim KP, et al

[DOI] [PubMed] [Google Scholar] 126.Xie Y., McGill M.R., Dorko K