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Although the specific connection between NRLP1 and vitiligo is not completely defined, it is likely that inflammasomes, including NRLP1, play an important role in the inflammatory and cell stress processes that characterize this disease.13,14 Type 1 interferon pathway (IFN type 1) The IFN-1 pathway is an early and transient link in disease progression and marks the junction point between the innate and adaptive immune response
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PMID: 9363866
Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1980 mg every 12 hours) or oral solution (2000 mg every 12 hours) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12 hours) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)
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