Given that free cuprous ions catalyse hydroxyl radical formation via the Fenton and HarberWeiss reactions [13, 17], hydrogen peroxide levels were measured in copper-treated cells
doi: 10.3389/fphar.2025.1599816 Received 25 March 2025 Accepted 16 June 2025 Published 22 July 2025 Volume 16 - 2025 Edited by Andrs Trostchansky, Universidad de la Repblica, Uruguay Reviewed by Satish Balasaheb Nimse, Hallym University, Republic of Korea Hctor Leonardo Montecino-Garrido, Center for Processed Food Studies, Chile Updates Copyright 2025 Tauchen, Huml, Jurek, Regenstein and Ozogul
This direct route ensures rapid and complete delivery, making them incredibly effective for quickly raising dangerously low B12 levels and managing severe symptoms
& Macklis, J
Serotypes such as AAV1, AAV6, AAV8, and especially AAV9 have demonstrated efficient cardiac transduction in small and large animals, enabling robust gene transfer to myocardium with intracoronary or intravenous delivery (Mazurek et al., 2024)