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Our data indicated that 797 transcripts were upregulated, and 1383 transcripts were downregulated in ESCC compared with the control (Figure 2a and Supplementary Table 1)

Introduction 1.1 Reactive oxygen species Reactive oxygen species (ROS), superoxide radicals (O 2 -), hydrogen peroxide (H 2 O 2 ), hydroxyl radical (OH-), and singlet oxygen are formed in normal oxygen metabolism

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