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Sparstolonin B suppresses free fatty acid palmitate-induced chondrocyte inflammation and mitigates post-traumatic arthritis in obese mice

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Mater Sci Eng R Rep 74:281350 Huang X, Qi X, Boey F, Zhang H (2012) Graphene-based composites

Structurally, it is the only GPX isoform with a monomeric conformation and a unique catalytic tetrad including Sec, Gln81, Trp136, and Asn137 that enables it to reduce complex hydroperoxides in situ even within membranes ( Transcriptionally, GPX4 expression is promoted by Nrf2 and ATF4 in response to oxidative or endoplasmic reticulum stress

It is believed to influence various bodily systems, especially the mucous membranes