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Ethical approval This study was approved by the Ethics Committee of the Plastic Surgery Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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75 A small controlled trial with 23 participants suffering from chronic tinnitus found tailor-made notched music training reduced activity in auditory brain regions and tinnitus loudness more effectively than placebo music training (with a varying notch in frequency range) or no treatment after six months and one year

10.1038/srep37589 99

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