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Mechanistically, it influences gene networks involved in tissue remodeling and exerts protective antioxidant and anti-inflammatory actions, partly through TGF- signaling and regulation of metalloproteinases

Three patients exhibit a mild response (the number of crises decrease of 33% for two patients and of 50% for the other one

Shim JH, Cho KJ, Lee KA, Kim SH, Myung PK, et al

If a patient has specific or red flag features B 12 deficiency testing should be initiated (see Figure 1: B 12 Test Result Review and Process Algorithm for Patients with Risk Factor for B 12 Deficiency * and/or Non-specific ** or Specific Symptom of B 12 Deficiency )

Huang Z-L, Zhang Z, Qu W-M (2014) Roles of adenosine and its receptors in sleepwake regulation