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Methods Construction of hexahistidine-tagged recombinant human GPx3 (rhGPx3) mutant expression vector A GPx3 mutant gene without signal peptide sequence (nucleic acids 160) was designed on the basis of the cDNA sequence of human GPx3 (GenBank accession No

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It is increased in acute inflammatory disorders and causes major changes in total plasma concentration of these drugs even though drug elimination is unchanged

Comparison with structures of the AMY 1 R bound to non-lipidated peptides (CagriBB and rAmy) revealed that the lipid conjugation does not affect the conformation of the peptide, nor the receptor when Cagri is stably engaged