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Sistema gastrointestinal : - Sikiric et al
Vitamin B12 has a good safety profile, but some important considerations include rare hypersensitivity reactions (including anaphylaxis) with injections, potential hypokalaemia during early treatment of severe deficiency, and possible cutaneous reactions
If you are considering starting B12 supplements, particularly at high doses, discuss this with your GP or a registered pharmacist, especially if you have existing medical conditions or take other medications
Because your body uses and excretes B12 rather than storing unlimited amounts, consistent timing helps keep your energy and focus steady instead of peaking and crashing. Many people find that taking B12 late in the day can make them feel more alert right when they are trying to wind down, which may interfere with sleep