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Leaky Gut and Barrier Function: Chronic gut inflammation can lead to increased intestinal permeability, often called 'leaky gut.' This allows bacteria and toxins to pass from the gut into the bloodstream, triggering even more inflammation systemically

Causes include hormone imbalance and genetic predisposition

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Mechanisms of Action Nootropics do not act directly by releasing neurotransmitters or as receptor ligands [16], but improve the brains supply of glucose and oxygen, have antihypoxic effects, and protect brain tissue from neurotoxicity [9,17]

Versari D, Daghini E, Virdis A, Ghiadoni L, Taddei S: Endothelium-dependent contractions and endothelial dysfunction in human hypertension