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In addition to filaggrin and the unique structure of the stratum corneum in the upper epidermis, tight junctions between keratinocytes also play a critical role in maintaining skin barrier integrity ( As the largest organ and a critical barrier separating the bodys internal environment from the external world, the skin is continuously exposed to various exogenous agents, leading to the generation of oxidative and inflammatory mediators ( The PI3K/AKT signaling cascade is a critical intracellular regulatory network that fundamentally governs cell proliferation, survival, metabolism, and immune response ( Topical glucocorticoids are commonly used as first-line anti-inflammatory agents in the management of AD

Iron deficiency affects your red blood cells, limiting the amount of oxygen your body can transport to the places where it's needed

This method allows for deeper penetration and increased bioavailability compared to topical creams and serums

doi: 10.1007/s11274-024-04085-w 120 LeeA.ChooH.JeonB

Skin brightening: Inhibits melanin production, reducing hyperpigmentation and dark spots