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Sierra et al., 2010)

10 An earlier study observed selective binding of two respiratory sensitizers exclusively to serum proteins, in contrast to two skin sensitizers which bound cellular proteins in the U937 cell line

To identify the proteins present, database searches of the extracted proteins unambiguously identified the 200 kDa protein and 100 kDa proteins in non-reduced and reduced samples, respectively, as transferrin receptor 1 (TfR1, gene name TFRC), a 200-180 kDa homo-dimeric, disulfide-linked protein

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